Online Software

ESDS

Welcome to "Enzyme Substrate Selectivity Intelligent Design System Software"! This software adopts the fully rational protease design and transformation method, through the method of site-directed mutagenesis, kinetic simulation, molecular docking and construction of mutation site screening scheme, to carry out fully rational design and transformation of enzyme molecules, thereby improving the performance of enzyme molecules.

ETSS

ETSS software is the open source software for the previous work of the project group. Based on the strategy of enzyme surface charge optimization, the Eij Energy Values before and after mutation were analyzed by calculating the contribution of single amino acid to the whole protein structure, to determine whether the mutation site enhances the thermal stability of the protein.