2022
Food Chemistry, Volume 374, 16 April 2022
Investigating mechanism of sweetness intensity differences through dynamic analysis of sweetener–T1R2–membrane systems
Yulu Miao, Hui Ni, Xingyi Zhang, Fengdong Zhi, Xiang Long, Xuepeng Yang, Xiao He*, Lujia Zhang*
LWT - Food Science and Technology, Volume 167, 15 September 2022
High-level expression and improved pepsin activity by enhancing the conserved domain stability based on a scissor-like model
Yue Zhao, Yulu Miao, Yalong Cong, Jiawei Wang, Fengdong Zhi, Yue Pan Jianguo Zhang, John Z.H. Zhang*, Lujia Zhang*
Frontiers in Molecular Biosciences, 23 May 2022
Rational Design of P450 aMOx for improving anti-Markovnikov selectivity based on Butterfly Model
Yue Pan, Jinxiao Bao, Xingyi Zhang, Hui Ni, Yue Zhao, Fengdong Zhi, Bohuan Fang, Xiao He*, John Z.H. Zhang*, Lujia Zhang*
Biomateries, Volume 287, August 2022
Umami polypeptide detection system targeting the human T1R1 receptor and its taste-presenting mechanism
Chuanxi Zhang, Yulu Miao, Yinghui Feng, Jiawei Wang, Zhuoli Tian, Juan Dong, Bei Gao*, Lujia Zhang*
2021
Food & Function, 21 May 2021
Drug-guided screening for pancreatic lipase inhibitors in functional foods
Lujia Zhang, Jinkai Zheng, Mingzhe Ma, Yue Zhao, Jia Song, Xin Chen, Wanxiu Cao, Xiao He, Changhu Xue, Qingjuan Tang*
Frontiers in Physics, 30 September 2021
Rational Design of Pepsin for Enhanced Thermostability via Exploiting the Guide of Structural Weakness Stability
Yue Zhao, Yulu Miao, Fengdong Zhi, Yue Pan, Jianguo Zhang, Xuepeng Yang, John Z. H. Zhang*, Lujia Zhang*
RSC Advances, 06 April 2021
Engineering the biomimetic cofactors of NMNH for cytochrome P450 BM3 based on binding conformation refinement
Yao Liu, Yalong Cong, Chuanxi Zhang, Bohuan Fang, Yue Pan, Qiangzi Li, Chun You, Bei Gao, John Z. H. Zhang, Tong Zhu*, Lujia Zhang*
Chemical Biology & Drug Design, February 2021
Identification of three new compounds that directly target human serine hydroxymethyltransferase 2
Yanfang Han, Liping He, Yifei Qi, Yue Zhao, Yue Pan, Bohuan Fang, Sha Li, John Z. H. Zhang*, Lujia Zhang*
Food Science & Nutrition, 03 May 2021
Investigation on the characteristics and mechanisms of ACE inhibitory peptides by a thorough analysis of all 8000 tripeptides via binding free energy calculation
Ruiyao Chen, Yulu Miao, Xuan Hao, Bei Gao, Mingzhe Ma, John Z. H. Zhang, Rui Wang, Sha Li, Xiao He*, Lujia Zhang*
Journal of Chemical Information and Modeling, 26 July 2021
Anchor-Locker Binding Mechanism of the Coronavirus Spike Protein to Human ACE2: Insights from Computational Analysis
Yalong Cong, Yinghui Feng, Hui Ni, Fengdong Zhi, Yulu Miao, Bohuan Fang, Lujia Zhang*, John Z. H. Zhang*
Journal of Molecular Biology, Volume 433, 25 June 2021
Programmed Flagellar Ejection in Caulobacter crescentus Leaves PL-subcomplexes
Mohammed Kaplan, Yuhang Wang, Georges Chreifi, Lujia Zhang, Yi-Wei Chang, Grant J. Jensen*
2020
Journal of Agricultural and Food Chemistry, 16 April 2020
An Energy Optimization Strategy Based on the Perfect Conformation of Prolyl Endopeptidase for Improving Catalytic6 Efficiency
Xiaolin Li, Yalong Cong, Mingzhe Ma, Zhineng You, Bei Gao, John Zeng Hui Zhang*, Lujia Zhang*
Proceedings of the National Academy of Sciences of the United States of America, 17 January 2020
M06-SX screened-exchange density functional for chemistry and solid-state physics
Ying Wang, Verma, Pragya, Lujia Zhang, Yaqi Li, Zhonghua Liu, Truhlar Donald G.*, Xiao He*
2020 before
Journal of Food Biochemistry, 04 October 2018
Identification and magnetic immobilization of a pyrophilous aspartic protease from Antarctic psychrophilic fungus
Bei Gao, Lei He, Dongzhi Wei, Lujia Zhang*
Protein Science, 03 May 2018
Crius: A novel fragment-based algorithm of de novo substrate prediction for enzymes
Zhiqiang Yao, Shuiqin Jiang, Lujia Zhang*, Bei Gao, Xiao He, John Z. H. Zhang, Dongzhi Wei*
Biochemical Engineering Journal, Volume 129, 15 January 2018
Energy and conformation determine the enantioselectivity of enzyme
Bei Gao, Shuiqin Jiang, Liuzhu Wang, Lujia Zhang* , Dongzhi Wei*
Catalysis Science & Technology, 15 February 2017
Switching a nitrilase from Syechocystis sp. PCC6803 to a nitrile hydratase by rationally regulating reaction pathways
Shuiqin Jiang, Lujia Zhang*, Zhiqiang Yao, Bei Gao, Hualei Wang, Xiangzhao Mao, Dongzhi Wei*
Food Chemistry, Volume 221, 15 April 2017
The structure features of umami hexapeptides for the T1R1/T1R3 receptor
Xiaqin Yu, Lujia Zhang*, Xiaodan Miao, Yanyu Li, Yuan Liu*
Journal of Chemical Information and Modeling, 23 August 2019
Study of SHMT2 Inhibitors and Their Binding Mechanism by Computational Alanine Scanning
Liping He, Jingxiao Bao, Yunpeng Yang, Suzhen Dong, Lujia Zhang, Yifei Qi*, John Z. H. Zhang*
Journal of Food Measurement and Characterization, 11 April 2019
Cloning, purification and biochemical characterization of recombinant Cathepsin L from Takifugu rubripes and its role in taste formation
Qilong Tang, Wenli Wang, Lujia Zhang, Yuan Liu*
Journal of Solid State Chemistry, Volume 272, April 2019
Syntheses, structures, optical properties, and electronic structures of Ba6Cu2GSn4S16 (G = Fe, Ni) and Sr6D2FeSn4S16 (D = Cu, Ag)
Lingyun Zhang, Dajiang Mei*, Yuanwang Wu, Chenfei Shen, Wenxin Hu, Lujia Zhang, Jinjin Li, Yuandong Wu, Xiao He
Applied Microbiology and Biotechnology, 06 December 2018
Structure-based design of agarase AgWH50C from Agarivorans gilvus WH0801 to enhance thermostability
Pujuan Zhang, Jinru Zhang, Lujia Zhang, Jianan Sun, Yuan Li, Lian Wu, Jiahai Zhou, Changhu Xue, Xiangzhao Mao*
Food Chemistry, Volume 245, 15 April 2018
Development and characterization of an α-L-rhamnosidase mutant with improved thermostability and a higher efficiency for debittering orange juice
Lijun Li, Zheyu Wu, Yue Yu, Lujia Zhang, Yanbing Zhu, Hui Ni*, Feng Chen
Journal of Agricultural and Food Chemistry, 18 January 2018
Antihypertensive effects, molecular docking study, and isothermal titration calorimetry assay of angiotensin I‑converting enzyme inhibitory peptides from Chlorella vulgaris
Jingli Xie*, Xujun Chen, Junjie Wu, Yanyan Zhang, Yan Zhou, Lujia Zhang, YaJie Tang, Dongzhi Wei*
BMC Biotechnology, 28 February 2017
Functional expression of a novel α-amylase from Antarctic psychrotolerant fungus for baking industry and its magnetic immobilization
Lei He, Youzhi Mao, Lujia Zhang, Hualei Wang, Siti Aisyah Alias, Bei Gao*, Dongzhi Wei
Scientific Reports, 17 October 2017
Novel application of magnetic protein: convenient one-step purification and immobilization of proteins
Min Jiang, Lujia Zhang, Fengqing Wang, Jie Zhang, Guosong Liu, Bei Gao*, Dongzhi Wei*
Journal of Agricultural and Food Chemistry, 27 August 2019
Biochemical Characterization and substrate degradation mode of a novel exotype β-agarase from Agarivorans gilvus WH0801
Yunxiao Liang, Xiaoqing Ma, Lujia Zhang, Fuli Li, Zhen Liu, Xiangzhao Mao*
Process Biochemistry, Volume 63, December 2017
Angiotensin I-converting enzyme inhibitory peptides from Sipuncula (Phascolosoma esculenta): purification, identification, molecular docking and antihypertensive effects on spontaneously hypertensive rats
Mingrong Guo, Xujun Chen, Yanling Wu, Lujia Zhang, Weixue Huang, Ying Yuan, Ming Fang, Jingli Xie*, Dongzhi Wei*
Chemical Physics Letters, Volume 685, 01 October 2017
Computational search for aflatoxin binding proteins
Ying Wang, Jinfeng Liu, Lujia Zhang, Xiao He*, John Z.H. Zhang*
Journal of Biotechnology, Volume 249, 10 May 2017
Identification of a novel phospholipase D with high transphosphatidylation activity and its application in synthesis of phosphatidylserine and DHA-phosphatidylserine
Xiangzhao Mao*, Qianqian Liu, Yongqian Qiu, Xiaoqin Fan, Qingqing Han, Yanjun Liu, Lujia Zhang, Changhu Xue*
Biotechnology for
Biofuels, 13 June 2016
Improvement of the
thermostability and catalytic efficiency of a highly active β-glucanase from Talaromyces
leycettanus JCM12802 by optimizing residual charge–charge interactions
Shuai You, Tao Tu, Lujia Zhang, Yuan Wang, Huoqing Huang, Rui Ma, Pengjun Shi,
Yingguo Bai, Xiaoyun Su, Zhemin Lin, Huiying Luo*, Bin Yao*
Scientific Reports, 06 October 2016
The important role of halogen bond in substrate selectivity of enzymatic catalysis
Shuiqin Jiang, LujiaZhang*, DongbinCui, ZhiqiangYao, BeiGao, Jinping Lin,
DongzhiWei*
Journal of Agricultural and Food Chemistry, 16 September 2016
Characterization of a Novel α- L -arabinofuranosidase from ruminococcus albus 7
and rational design for its thermostability
Ying Yang, Jiaqi Sun, Junjie Wu, Lujia Zhang, Lei Du,Shingo Matsukawa, Jingli Xie*,
Dongzhi Wei
Journal of Chemical
Information and Modeling, 16 August 2016
A semi-automated structure-based method to predict substrate of enzyme
via molecular docking: a case study with Candida antarctica Lipase B
Zhiqiang Yao, Lujia Zhang*, Bei Gao, Dongbing Cui, Fengqing Wang, Xiao He,John Z. H.
Zhang, Dongzhi Wei*
Chemical Physics Letters, Volume 659, 16 August 2016
Predicted
PAR1 inhibitors from multiple computational methods
Ying Wang, Jinfeng Liu, Tong Zhu, Lujia Zhang, Xiao He*, John Z.H. Zhang*
Journal of Chemical
Information and Modeling, Volume 56, 18 April 2016
PBSA_E: a
PBSA-based free energy estimator for protein-ligand binding affinity
Xiao Liu, Jinfeng Liu, Tong Zhu, Lujia Zhang, Xiao He*, John Z. H. Zhang*
Applied and
Environmental Microbiology, 13 November 2015
Protein engineering of a nitrilase from Burkholderia cenocepacia J2315 for
efficient and enantioselective production of (R)-o-chloromandelic acid
Hualei Wang, Wenyuan Gao, Huihui Sun, Lifeng Chen, Lujia Zhang, Xuedong Wang*,
Dongzhi Wei*
Applied and Environmental Microbiology, 4 September 2015
Improvement in thermostability of an
Achaetomium sp. strain Xz8 endopolygalacturonase via the optimization of charge-charge
interactions
Tao Tu, Huiying Luo, Kun Meng, Yanli Cheng, Rui Ma, Pengjun Shi, Huoqing Huang, Yingguo Bai, Yaru Wang, Lujia Zhang*, Bin Yao*
Plos One, 01 September 2015
New insights into the role of T3 loop
in determining catalytic efficiency of GH28 endo-polygalacturonases
Tao Tu, Kun Meng, Huiying Luo, Ossi Turunen, Lujia Zhang, Yanli Cheng, Xiaoyun Su, Rui Ma, Pengjun Shi, Yaru Wang, Peilong Yang, Bin Yao*
Starch-Starke, 26 August 2015
A novel saccharifying a-
amylase of Antarctic psychrotolerant fungi Geomyces pannorum: gene cloning, functional
expression, and characterization
Bei Gao, Youzhi Mao, Lujia Zhang*, Lei He, Dongzhi Wei
Process Biochemistry, Volume 50, October 2015
Development of a novel Aspergillus uracil deficient expression system and its application in
expressing a cold-adapted α-amylase gene from Antarctic fungi Geomyces pannorum
Youzhi Mao, Yanchen Yin, Lujia Zhang, Siti Aisyah Alias, BeiGao*, DongzhiWei
Journal of Agricultural and Food
Chemistry, 23 March 2015
Novel α-L-Arabinofuranosidase from Cellulomonas fimi ATCC 484 and its
substrate -specificity analysis with the aid of computer
Ying Yang, Lujia Zhang, Mingrong Guo, Jiaqi Sun, Shingo Matsukawa, Jingli Xie*,
Dongzhi Wei
Febs Journal, 28 March 2015
A computational strategy for altering an enzyme in its cofactor preference
to NAD(H) and/or NADP(H)
Dongbing Cui, Lujia Zhang*, Shuiqin Jiang, Zhiqiang Yao, Bei Gao, Jinping Lin, Y. Adam
Yuan, Dongzhi Wei*
BMC Biotechnol, 24 December 2014
Cloning of a novel thermostable glucoamylase from thermophilic fungus
Rhizomucor pusillus and high-level co-expression with α-amylase in Pichia pastoris
Zhenggui He, Lujia Zhang, Youzhi Mao, Jingchao Gu, Qi Pan, Sixing Zhou, Bei Gao*,
Dongzhi Wei*
Proteins, 13 May 2014
Structural insights into substrate and coenzyme preference by SDR family protein
Gox2253 from Gluconobater oxydans
Bo Yin, Dongbing Cui, Lujia Zhang, Shuiqin Jiang, Satoru Machida, Y. Adam Yuan*,
Dongzhi Wei*
Protein science, 11 August 2014
Structural and mutational studies on an aldo-keto reductase
AKR5C3 from Gluconobacter oxydans
Xu Liu, Chao Wang, Lujia Zhang, Zhiqiang Yao, Dongbing Cui, Liang Wu, Jinping Lin*,
YuRen Adam Yuan*, Dongzhi Wei
Journal of Structural Biology, Volume 188, November 2014
Structural insights into enzymatic activity and substrate specificity determination
by a single amino acid in nitrilase from Syechocystis sp. PCC6803
Lujia Zhang#, Bo Yin#, Chao Wang, Shuiqin Jiang, Hualei Wang, Y. Adam Yuan*,
Dongzhi Wei*
Bioresources and Bioprocessing, 09 October 2014
Virtual
screening for angiotensin I-converting enzyme inhibitory peptides from Phascolosoma esculenta
Yalan Liu, Lujia Zhang, Mingrong Guo, Hongxi Wu, Jingli Xie*, Dongzhi Wei
Process Biochem, Volume 49, May 2014
In vitro and in vivo ACE inhibitory of pistachio hydrolysates and in silico
mechanism of identified peptide binding with ACE
Peng Li, Jia Jia, Ming Fang, Lujia Zhang, Mingrong Guo, Jingli Xie*, Yuelan Xia, Li Zhou,
Dongzhi Wei
BBA-proteins and Proteomics, Volume 1844, July 2014
Structure, mechanism, and enantioselectivity shifting of lipase LipK107 with a
simple way
Lujia Zhang, Bei Gao, Zuanning Yuan, Xiao He, Y. Adam Yuan, John Z.H. Zhang*, Dongzhi Wei*
Protein science, 29 October 2013
A method to rationally increase protein stability based on
the charge-charge interaction, with application to lipase LipK107
Lujia Zhang, Xiaomang Tang, Dongbing Cui, Zhiqiang Yao, Bei Gao, Shuiqin Jiang, Bo Yin, Y. Adam Yuan*, Dongzhi Wei*
Journal of Biotechnology, Volume 167, 20 September 2013
Computational design of short-chain dehydrogenase Gox2181 for altered
coenzyme specificity
Dongbing Cui, Lujiang Zhang*, Zhiqiang Yao, Xu Liu, Jinping Lin, Y. Adam Yuan, Dongzhi Wei*
Journal of Agricultural and Food Chemistry, 22 February 2013
Purification
of xylitol dehydrogenase and improved production of xylitol by increasing XDH activity and
NADH supply in Gluconobacter oxydans
Jinliang Zhang, Sha Li, Hong Xu*, Peng Zhou, Lujia Zhang, Pingkai Ouyang
Biochimie, Volume 94, June 2012
Structure-
based characterization of canine-human chimeric uricases and its evolutionary implications
Chun Zhang, Kai Fan, Weitao Zhang, Ruixin Zhu, Lujia Zhang, Dongzhi Wei*
Journal of Molecular Catalysis B:
enzymatic, Volume 71, September 2011
Construction of a whole-cell catalyst displaying a fungal
lipase for effective treatment of oily wastewaters
Huiting Song, Lichao Zhou, Lujia Zhang, Bei Gao, Dongzhi Wei, Yaling Shen, Rui Wang, Catherine Madzak, Zhengbing Jiang*
Journal of Molecular Catalysis B:
enzymatic, Volume 68, March 2011
Improving the catalytic activity of lipase LipK107 from Proteus sp. by site-directed mutagenesis
in the lid domain based on computer simulation
Bei Gao, Tao Xu, Jinping Lin, Lujia Zhang, Erzheng Su, Zhengbing Jiang, Dongzhi Wei*
Biochimica ET Biophysica ACTA-Proteins and Proteomics, Volume 1804, December 2010
Template-
based modeling of a psychrophilic lipase: conformational changes, novel structural features and its
application in predicting the enantioselectivity of lipase catalyzed transesterification of secondary alcohols
Tao Xu, Bei Gao, Lujia Zhang, Jingpin Lin, Xuedong Wang, Dongzhi Wei*
Molecular Simulation, 24 November 2010
A novel protocol of energy
optimisation for predicted protein structures built by homology modelling
Tao Xu, Lujia Zhang, Xuedong Wang, Dongzhi Wei*
Journal of Molecular Catalysis B:
enzymatic, Volume 62, March 2010
Disparity in productive binding mode of the slow-reacting enantiomer determines the novel
catalytic behavior of Candida antarctica lipase B
Tao Xu, Lujia Zhang, Erzheng Su, Dongbing Cui, Xuedong Wang*, Dongzhi Wei*
BMC Bioinformatics, 21 August 2009
Structure-based substrate
screening for an enzym
Tao Xu, Lujia Zhang, Xuedong Wang*, Dongzhi Wei*
